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TIMP3 is a CLOCK-dependent diurnal gene that inhibits the expression of UVB-induced inflammatory cytokines in human keratinocytes

As the outermost physical barrier of an organism, the skin is diurnally exposed to UV radiation (UVR). Recent studies have revealed that the skin exhibits a circadian rhythm in various functions, and this oscillation is disturbed and reset via a strong environmental cue, the UVR. However, a molecula...

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Detalles Bibliográficos
Autores principales: Park, Sunyoung, Kim, Kyuhan, Bae, Il-Hong, Lee, Sung Hoon, Jung, Jiyong, Lee, Tae Ryong, Cho, Eun-Gyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892724/
https://www.ncbi.nlm.nih.gov/pubmed/29180440
http://dx.doi.org/10.1096/fj.201700693R