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Predicting essential proteins by integrating orthology, gene expressions, and PPI networks
Identifying essential proteins is very important for understanding the minimal requirements of cellular life and finding human disease genes as well as potential drug targets. Experimental methods for identifying essential proteins are often costly, time-consuming, and laborious. Many computational...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892885/ https://www.ncbi.nlm.nih.gov/pubmed/29634727 http://dx.doi.org/10.1371/journal.pone.0195410 |