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High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development

The microtubule associated protein tau plays a critical role in the pathogenesis of neurodegenerative disease. Recent studies suggest that tau also plays a role in disorders of neuronal connectivity, including epilepsy and post-traumatic stress disorder. Animal studies have shown that the MAPT gene,...

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Detalles Bibliográficos
Autores principales: Hefti, Marco M., Farrell, Kurt, Kim, SoongHo, Bowles, Kathryn R., Fowkes, Mary E., Raj, Towfique, Crary, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892924/
https://www.ncbi.nlm.nih.gov/pubmed/29634760
http://dx.doi.org/10.1371/journal.pone.0195771