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High-resolution temporal and regional mapping of MAPT expression and splicing in human brain development
The microtubule associated protein tau plays a critical role in the pathogenesis of neurodegenerative disease. Recent studies suggest that tau also plays a role in disorders of neuronal connectivity, including epilepsy and post-traumatic stress disorder. Animal studies have shown that the MAPT gene,...
Autores principales: | Hefti, Marco M., Farrell, Kurt, Kim, SoongHo, Bowles, Kathryn R., Fowkes, Mary E., Raj, Towfique, Crary, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892924/ https://www.ncbi.nlm.nih.gov/pubmed/29634760 http://dx.doi.org/10.1371/journal.pone.0195771 |
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