Selective inhibition of histamine-evoked Ca(2+) signals by compartmentalized cAMP in human bronchial airway smooth muscle cells

Intracellular Ca(2+) and cAMP typically cause opposing effects on airway smooth muscle contraction. Receptors that stimulate these pathways are therapeutic targets in asthma and chronic obstructive pulmonary disease. However, the interactions between different G protein-coupled receptors (GPCRs) tha...

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Detalles Bibliográficos
Autores principales: Dale, Philippa, Head, Victoria, Dowling, Mark R., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893132/
https://www.ncbi.nlm.nih.gov/pubmed/29604964
http://dx.doi.org/10.1016/j.ceca.2017.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893132/
https://www.ncbi.nlm.nih.gov/pubmed/29604964
http://dx.doi.org/10.1016/j.ceca.2017.12.002

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