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Nephron segment-specific gene expression using AAV vectors
AAV9 vector provides efficient gene transfer in all segments of the renal nephron, with minimum expression in non-renal cells, when administered retrogradely via the ureter. It is important to restrict the transgene expression to the desired cell type within the kidney, so that the physiological end...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893140/ https://www.ncbi.nlm.nih.gov/pubmed/29407172 http://dx.doi.org/10.1016/j.bbrc.2018.01.169 |