IDH1 mutation is associated with lower expression of VEGF but not microvessel formation in glioblastoma multiforme

INTRODUCTION: Glioblastoma multiforme (GBM) represents the most malignant primary brain tumor characterized by pathological vascularization. Mutations in isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) were observed in GBM. We aimed to assess the intra-tumor hypoxia, angiogenesis and microvessel f...

Descripción completa

Detalles Bibliográficos
Autores principales: Polívka, Jiří, Pešta, Martin, Pitule, Pavel, Hes, Ondřej, Holubec, Luboš, Kubíková, Tereza, Tonar, Zbyněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893254/
https://www.ncbi.nlm.nih.gov/pubmed/29662659
http://dx.doi.org/10.18632/oncotarget.24536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893254/
https://www.ncbi.nlm.nih.gov/pubmed/29662659
http://dx.doi.org/10.18632/oncotarget.24536

Ejemplares similares