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IDH1 mutation is associated with lower expression of VEGF but not microvessel formation in glioblastoma multiforme

INTRODUCTION: Glioblastoma multiforme (GBM) represents the most malignant primary brain tumor characterized by pathological vascularization. Mutations in isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) were observed in GBM. We aimed to assess the intra-tumor hypoxia, angiogenesis and microvessel f...

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Detalles Bibliográficos
Autores principales:	Polívka, Jiří, Pešta, Martin, Pitule, Pavel, Hes, Ondřej, Holubec, Luboš, Kubíková, Tereza, Tonar, Zbyněk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893254/ https://www.ncbi.nlm.nih.gov/pubmed/29662659 http://dx.doi.org/10.18632/oncotarget.24536

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