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Melatonin Modifies Histone Acetylation during In Vitro Maturation of Mouse Oocytes

OBJECTIVE: We evaluated the effect of melatonin, as a potent antioxidant agent, on glutathione (GSH) and reactive oxygen species (ROS) levels, as well as histone H3 lysine 9 (H3K9), and H4 lysine 12 (H4K12) acetylation when added to oocytes culture medium. MATERIALS AND METHODS: In this experimental...

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Detalles Bibliográficos
Autores principales: Keshavarzi, Somayeh, Salehi, Mohammad, Farifteh-Nobijari, Fattaneh, Hosseini, Taher, Hosseini, Sara, Ghazifard, Alaleh, Ghaffari Novin, Marefat, Fallah-Omrani, Vahid, Nourozian, Mohsen, Hosseini, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893296/
https://www.ncbi.nlm.nih.gov/pubmed/29633602
http://dx.doi.org/10.22074/cellj.2018.4860