EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration

Microtubules have long been implicated to play an integral role in metastatic disease, for which a critical step is the local invasion of tumor cells into the 3-dimensional (3D) collagen-rich stromal matrix. Here we show that cell migration of human cancer cells uses the dynamic formation of highly...

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Detalles Bibliográficos
Autores principales: Jayatilaka, Hasini, Giri, Anjil, Karl, Michelle, Aifuwa, Ivie, Trenton, Nicholaus J., Phillip, Jude M., Khatau, Shyam, Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893312/
https://www.ncbi.nlm.nih.gov/pubmed/29097501
http://dx.doi.org/10.1096/fj.201700444RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893312/
https://www.ncbi.nlm.nih.gov/pubmed/29097501
http://dx.doi.org/10.1096/fj.201700444RR

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