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EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration
Microtubules have long been implicated to play an integral role in metastatic disease, for which a critical step is the local invasion of tumor cells into the 3-dimensional (3D) collagen-rich stromal matrix. Here we show that cell migration of human cancer cells uses the dynamic formation of highly...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Federation of American Societies for Experimental Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893312/ https://www.ncbi.nlm.nih.gov/pubmed/29097501 http://dx.doi.org/10.1096/fj.201700444RR |