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The HIV protease and PI3K/Akt inhibitor nelfinavir does not improve the curative effect of fractionated irradiation in PC-3 prostate cancer in vitro and in vivo

BACKGROUND: Radiotherapy has a high curative potential in localized prostate cancer, however, there are still patients with locally advanced tumours who face a considerable risk of recurrence. Radiosensitization using molecular targeted drugs could help to optimize treatment for this high-risk group...

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Detalles Bibliográficos
Autores principales: Liebscher, Steffi, Koi, Lydia, Löck, Steffen, Muders, Michael H., Krause, Mechthild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893532/
https://www.ncbi.nlm.nih.gov/pubmed/29657993
http://dx.doi.org/10.1016/j.ctro.2016.12.002