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ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms

We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline followed...

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Detalles Bibliográficos
Autores principales: Iacobaş, Dumitru A., Chachua, Tamar, Iacobaş, Sanda, Benson, Melissa J., Borges, Karin, Velíšková, Jana, Velíšek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893534/
https://www.ncbi.nlm.nih.gov/pubmed/29636502
http://dx.doi.org/10.1038/s41598-018-24013-x