Small tumor necrosis factor receptor biologics inhibit the tumor necrosis factor-p38 signalling axis and inflammation

Despite anti-TNF therapy advancements for inflammatory diseases such as rheumatoid arthritis, the burden of diseases remains high. An 11-mer TNF peptide, TNF(70–80), is known to stimulate selective functional responses compared to the parent TNF molecule. Here, we show that TNF(70–80) binds to the T...

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Detalles Bibliográficos
Autores principales: Mukaro, Violet R., Quach, Alex, Gahan, Michelle E., Boog, Bernadette, Huang, Zhi H., Gao, Xiuhui, Haddad, Carol, Mahalingam, Suresh, Hii, Charles S., Ferrante, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893557/
https://www.ncbi.nlm.nih.gov/pubmed/29636466
http://dx.doi.org/10.1038/s41467-018-03640-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893557/
https://www.ncbi.nlm.nih.gov/pubmed/29636466
http://dx.doi.org/10.1038/s41467-018-03640-y

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