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Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo
A cell therapy platform permitting long-term delivery of peptide hormones in vivo would be a significant advance for patients with hormonal deficiencies. Here we report the utility of antigen-specific T lymphocytes as a regulatable peptide delivery platform for in vivo therapy. piggyBac transposon m...
Autores principales: | O’Neil, Richard T., Saha, Sunandan, Veach, Ruth Ann, Welch, Richard C., Woodard, Lauren E., Rooney, Cliona M., Wilson, Matthew H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893599/ https://www.ncbi.nlm.nih.gov/pubmed/29636469 http://dx.doi.org/10.1038/s41467-018-03787-8 |
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