Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models

Feingold syndrome is a skeletal dysplasia caused by loss-of-function mutations of either MYCN (type 1) or MIR17HG that encodes miR-17-92 microRNAs (type 2). Since miR-17-92 expression is transcriptionally regulated by MYC transcription factors, it has been postulated that Feingold syndrome type 1 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Mirzamohammadi, Fatemeh, Kozlova, Anastasia, Papaioannou, Garyfallia, Paltrinieri, Elena, Ayturk, Ugur M., Kobayashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893605/
https://www.ncbi.nlm.nih.gov/pubmed/29636449
http://dx.doi.org/10.1038/s41467-018-03788-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893605/
https://www.ncbi.nlm.nih.gov/pubmed/29636449
http://dx.doi.org/10.1038/s41467-018-03788-7

Ejemplares similares