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Analysis of HIV-1 envelope evolution suggests antibody-mediated selection of common epitopes among Chinese former plasma donors from a narrow-source outbreak

The HIV-1 envelope mutates rapidly to evade recognition and killing, and is a major target of humoral immune responses and vaccine development. Identification of common epitopes for vaccine development have been complicated by genetic variation on both virus and host levels. We studied HIV-1 envelop...

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Detalles Bibliográficos
Autores principales: Andrews, Sophie M., Zhang, Yonghong, Dong, Tao, Rowland-Jones, Sarah L., Gupta, Sunetra, Esbjörnsson, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893620/
https://www.ncbi.nlm.nih.gov/pubmed/29636501
http://dx.doi.org/10.1038/s41598-018-23913-2