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Analysis of HIV-1 envelope evolution suggests antibody-mediated selection of common epitopes among Chinese former plasma donors from a narrow-source outbreak
The HIV-1 envelope mutates rapidly to evade recognition and killing, and is a major target of humoral immune responses and vaccine development. Identification of common epitopes for vaccine development have been complicated by genetic variation on both virus and host levels. We studied HIV-1 envelop...
Autores principales: | Andrews, Sophie M., Zhang, Yonghong, Dong, Tao, Rowland-Jones, Sarah L., Gupta, Sunetra, Esbjörnsson, Joakim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893620/ https://www.ncbi.nlm.nih.gov/pubmed/29636501 http://dx.doi.org/10.1038/s41598-018-23913-2 |
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