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GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway

ViscumTT, a whole mistletoe preparation, has shown synergistic induction of apoptosis in several pediatric tumor entities. High therapeutic potential has previously been observed in Ewing’s sarcoma, rhabdomyosarcoma, ALL and AML. In this study, we analyzed modulatory effects on the cell cycle by vis...

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Detalles Bibliográficos
Autores principales: Kleinsimon, Susann, Longmuss, Enya, Rolff, Jana, Jäger, Sebastian, Eggert, Angelika, Delebinski, Catharina, Seifert, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893628/
https://www.ncbi.nlm.nih.gov/pubmed/29636527
http://dx.doi.org/10.1038/s41598-018-24075-x