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Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination

Effective priming and activation of tumor-specific CD8+ cytotoxic T lymphocytes (CTLs) is crucial for realizing the potential of therapeutic cancer vaccination. This requires cytosolic antigens that feed into the MHC class I presentation pathway, which is not efficiently achieved with most current v...

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Detalles Bibliográficos
Autores principales: Haug, Markus, Brede, Gaute, Håkerud, Monika, Nedberg, Anne Grete, Gederaas, Odrun A., Flo, Trude H., Edwards, Victoria T., Selbo, Pål K., Høgset, Anders, Halaas, Øyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893651/
https://www.ncbi.nlm.nih.gov/pubmed/29670624
http://dx.doi.org/10.3389/fimmu.2018.00650