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Adipose tissue, but not skeletal muscle, sirtuin 1 expression is decreased in obesity and related to insulin sensitivity

PURPOSE: Sirtuin 1 may regulate glucose and lipid metabolism. We aimed to assess adipose tissue and skeletal muscle sirtuin 1 expression in relation to insulin sensitivity, the expression of proinflammatory and metabolic genes, and to study the regulation of sirtuin 1 expression by hyperinsulinemia...

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Detalles Bibliográficos
Autores principales: Stefanowicz, Magdalena, Nikołajuk, Agnieszka, Matulewicz, Natalia, Karczewska-Kupczewska, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893655/
https://www.ncbi.nlm.nih.gov/pubmed/29417372
http://dx.doi.org/10.1007/s12020-018-1544-1