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Adipose tissue, but not skeletal muscle, sirtuin 1 expression is decreased in obesity and related to insulin sensitivity
PURPOSE: Sirtuin 1 may regulate glucose and lipid metabolism. We aimed to assess adipose tissue and skeletal muscle sirtuin 1 expression in relation to insulin sensitivity, the expression of proinflammatory and metabolic genes, and to study the regulation of sirtuin 1 expression by hyperinsulinemia...
Autores principales: | Stefanowicz, Magdalena, Nikołajuk, Agnieszka, Matulewicz, Natalia, Karczewska-Kupczewska, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893655/ https://www.ncbi.nlm.nih.gov/pubmed/29417372 http://dx.doi.org/10.1007/s12020-018-1544-1 |
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