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Divergent Mitochondrial Antioxidant Activities and Lung Alveolar Architecture in the Lungs of Rats and Mice at High Altitude

Compared with mice, adult rats living at 3,600 m above sea level (SL—La Paz, Bolivia) have high hematocrit, signs of pulmonary hypertension, and low lung volume with reduced alveolar surface area. This phenotype is associated with chronic mountain sickness in humans living at high altitude (HA). We...

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Detalles Bibliográficos
Autores principales: Jochmans-Lemoine, Alexandra, Revollo, Susana, Villalpando, Gabriella, Valverde, Ibana, Gonzales, Marcelino, Laouafa, Sofien, Soliz, Jorge, Joseph, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893716/
https://www.ncbi.nlm.nih.gov/pubmed/29670534
http://dx.doi.org/10.3389/fphys.2018.00311