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The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APP(swe) Cell Model of AD

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that has proved refractory to drug treatment. Given evidence of neuroprotection in animal models of ischemic stroke, we assessed the prenylflavonoid xanthohumol from the Common Hop (Humulus lupulus L.) for therapeutic potential in...

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Detalles Bibliográficos
Autores principales: Huang, Xianfeng, Wang, Jing, Chen, Xiao, Liu, Pan, Wang, Shujin, Song, Fangchen, Zhang, Zaijun, Zhu, Feiqi, Huang, Xinfeng, Liu, Jianjun, Song, Guoqiang, Spencer, Peter S., Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893754/
https://www.ncbi.nlm.nih.gov/pubmed/29670521
http://dx.doi.org/10.3389/fphar.2018.00199