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The Prenylflavonoid Xanthohumol Reduces Alzheimer-Like Changes and Modulates Multiple Pathogenic Molecular Pathways in the Neuro2a/APP(swe) Cell Model of AD
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that has proved refractory to drug treatment. Given evidence of neuroprotection in animal models of ischemic stroke, we assessed the prenylflavonoid xanthohumol from the Common Hop (Humulus lupulus L.) for therapeutic potential in...
Autores principales: | Huang, Xianfeng, Wang, Jing, Chen, Xiao, Liu, Pan, Wang, Shujin, Song, Fangchen, Zhang, Zaijun, Zhu, Feiqi, Huang, Xinfeng, Liu, Jianjun, Song, Guoqiang, Spencer, Peter S., Yang, Xifei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893754/ https://www.ncbi.nlm.nih.gov/pubmed/29670521 http://dx.doi.org/10.3389/fphar.2018.00199 |
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