CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma

BACKGROUND: HPV infection is associated with high p16 expression and good prognosis in head and neck squamous cell carcinomas (HNSCCs). Analysis of CDKN2A, the gene encoding p16, may further elucidate the association between p16 expression and prognosis. We sought to determine whether CDKN2A copy nu...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, William S., Bindra, Ranjit S., Mo, Allen, Hayman, Thomas, Husain, Zain, Contessa, Joseph N., Gaffney, Stephen G., Townsend, Jeffrey P., Yu, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893829/
https://www.ncbi.nlm.nih.gov/pubmed/29670856
http://dx.doi.org/10.3389/fonc.2018.00095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893829/
https://www.ncbi.nlm.nih.gov/pubmed/29670856
http://dx.doi.org/10.3389/fonc.2018.00095

Ejemplares similares