An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance

Polymyxins, a family of cationic antimicrobial cyclic peptides, act as a last line of defense against severe infections by Gram-negative pathogens with carbapenem resistance. In addition to the intrinsic resistance to polymyxin E (colistin) conferred by Neisseria eptA, the plasmid-borne mobilized co...

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Detalles Bibliográficos
Autores principales: Xu, Yongchang, Wei, Wenhui, Lei, Sheng, Lin, Jingxia, Srinivas, Swaminath, Feng, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893884/
https://www.ncbi.nlm.nih.gov/pubmed/29636432
http://dx.doi.org/10.1128/mBio.02317-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893884/
https://www.ncbi.nlm.nih.gov/pubmed/29636432
http://dx.doi.org/10.1128/mBio.02317-17

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