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Role of B-cell receptors for B-cell development and antigen-induced differentiation

B-cell development is characterized by a number of tightly regulated selection processes. Signals through the B-cell receptor (BCR) guide and are required for B-cell maturation, survival, and fate decision. Here, we review the role of the BCR during B-cell development, leading to the emergence of B1...

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Detalles Bibliográficos
Autores principales: Yam-Puc, Juan Carlos, Zhang, Lingling, Zhang, Yang, Toellner, Kai-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893946/
https://www.ncbi.nlm.nih.gov/pubmed/30090624
http://dx.doi.org/10.12688/f1000research.13567.1