Induction of immunity following vaccination with a chemically attenuated malaria vaccine correlates with persistent antigenic stimulation

OBJECTIVES: Blood stage malaria parasites attenuated with seco‐cyclopropyl pyrrolo indole (CPI) analogues induce robust immunity in mice to homologous and heterologous malaria parasites and are being considered for the development of a human vaccine. However, it is not understood how attenuated para...

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Detalles Bibliográficos
Autores principales: Reiman, Jennifer M, Kumar, Sanjai, Rodriguez, Ingrid B, Gnidehou, Sedami, Ito, Koichi, Stanisic, Danielle I, Lee, Moses, McPhun, Virginia, Majam, Victoria, Willemsen, Nicole M, Batzloff, Michael R, Raja, Amber I, Dooley, Brad, Hoffman, Stephen L, Yanow, Stephanie K, Good, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894007/
https://www.ncbi.nlm.nih.gov/pubmed/29670745
http://dx.doi.org/10.1002/cti2.1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894007/
https://www.ncbi.nlm.nih.gov/pubmed/29670745
http://dx.doi.org/10.1002/cti2.1015

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