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Hidden Structural Modules in a Cooperative RNA Folding Transition

Large-scale, cooperative rearrangements underlie the functions of RNA in RNA-protein machines and gene regulation. To understand how such rearrangements are orchestrated, we used high-throughput chemical footprinting to dissect a seemingly concerted rearrangement in P5abc RNA, a paradigm of RNA fold...

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Detalles Bibliográficos
Autores principales: Gracia, Brant, Al-Hashimi, Hashim M., Bisaria, Namita, Das, Rhiju, Herschlag, Daniel, Russell, Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894117/
https://www.ncbi.nlm.nih.gov/pubmed/29562180
http://dx.doi.org/10.1016/j.celrep.2018.02.101