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Hidden Structural Modules in a Cooperative RNA Folding Transition
Large-scale, cooperative rearrangements underlie the functions of RNA in RNA-protein machines and gene regulation. To understand how such rearrangements are orchestrated, we used high-throughput chemical footprinting to dissect a seemingly concerted rearrangement in P5abc RNA, a paradigm of RNA fold...
Autores principales: | Gracia, Brant, Al-Hashimi, Hashim M., Bisaria, Namita, Das, Rhiju, Herschlag, Daniel, Russell, Rick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894117/ https://www.ncbi.nlm.nih.gov/pubmed/29562180 http://dx.doi.org/10.1016/j.celrep.2018.02.101 |
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