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Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes

BACKGROUND: Osteoclasts have been strongly implicated in osteoarthritic cartilage degradation, at least indirectly via bone resorption, and have been shown to degrade cartilage in vitro. The osteoclast resorption processes required to degrade subchondral bone and cartilage—the remodeling of which is...

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Detalles Bibliográficos
Autores principales: Löfvall, Henrik, Newbould, Hannah, Karsdal, Morten A., Dziegiel, Morten H., Richter, Johan, Henriksen, Kim, Thudium, Christian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894194/
https://www.ncbi.nlm.nih.gov/pubmed/29636095
http://dx.doi.org/10.1186/s13075-018-1564-5