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GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2

BACKGROUND: Growth differentiation factor 15 (GDF15) is a member of the TGF-β superfamily, and evidence suggests that a substantial amount of GDF15 is secreted in various human cancers, such as ovarian cancer, prostate cancer, and breast cancer, among others. However, the function of GDF15 in cervic...

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Detalles Bibliográficos
Autores principales: Li, Shan, Ma, Yan-Min, Zheng, Peng-Sheng, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894198/
https://www.ncbi.nlm.nih.gov/pubmed/29636108
http://dx.doi.org/10.1186/s13046-018-0744-0