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Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis

BACKGROUND: Anticitrullinated protein antibodies (ACPA) and citrullinated proteins play key roles in the pathogenesis of rheumatoid arthritis (RA). Many candidate citrullinated antigens have been identified in joints, but citrullinated proteins in sera are mostly uncertain in patients with RA. We ex...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Hoshimi, Matsumoto, Isao, Osada, Atsumu, Kurata, Izumi, Ebe, Hiroshi, Tanaka, Yuki, Inoue, Asuka, Umeda, Naoto, Kondo, Yuya, Tsuboi, Hiroto, Shinkai, Yasuhiro, Kumagai, Yoshito, Ishigami, Akihito, Sumida, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894205/
https://www.ncbi.nlm.nih.gov/pubmed/29636082
http://dx.doi.org/10.1186/s13075-018-1562-7