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Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis
BACKGROUND: Anticitrullinated protein antibodies (ACPA) and citrullinated proteins play key roles in the pathogenesis of rheumatoid arthritis (RA). Many candidate citrullinated antigens have been identified in joints, but citrullinated proteins in sera are mostly uncertain in patients with RA. We ex...
Autores principales: | Kawaguchi, Hoshimi, Matsumoto, Isao, Osada, Atsumu, Kurata, Izumi, Ebe, Hiroshi, Tanaka, Yuki, Inoue, Asuka, Umeda, Naoto, Kondo, Yuya, Tsuboi, Hiroto, Shinkai, Yasuhiro, Kumagai, Yoshito, Ishigami, Akihito, Sumida, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894205/ https://www.ncbi.nlm.nih.gov/pubmed/29636082 http://dx.doi.org/10.1186/s13075-018-1562-7 |
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