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Comparison of Albendazole Cytotoxicity in Terms of Metabolite Formation in Four Model Systems

INTRODUCTION: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone. However, it is not clear which compound is responsible for toxic effects...

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Detalles Bibliográficos
Autores principales: Radko, Lidia, Minta, Maria, Jedziniak, Piotr, Stypuła-Tręba, Sylwia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894428/
https://www.ncbi.nlm.nih.gov/pubmed/29978089
http://dx.doi.org/10.1515/jvetres-2017-0042