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Comparison of Albendazole Cytotoxicity in Terms of Metabolite Formation in Four Model Systems
INTRODUCTION: Albendazole is used to treat endoparasitic diseases in animals and humans. After oral administration, it is quickly oxidised into its pharmacologically active metabolite albendazole sulfoxide and then to sulfone. However, it is not clear which compound is responsible for toxic effects...
Autores principales: | Radko, Lidia, Minta, Maria, Jedziniak, Piotr, Stypuła-Tręba, Sylwia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter Open
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894428/ https://www.ncbi.nlm.nih.gov/pubmed/29978089 http://dx.doi.org/10.1515/jvetres-2017-0042 |
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