Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis

Triptolide (TP) exhibits immunosuppressive, cartilage-protective and anti-inflammatory effects in rheumatoid arthritis. However, the toxicity of TP limits its widespread use. To decrease the toxic effects, we developed a novel nano-drug carrier system containing TP using poly-γ-glutamic acid-grafted...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Chang, Junli, Zhao, Yongjian, Xu, Hao, Wang, Tengteng, Li, Qiang, Xing, Lianping, Huang, Jing, Wang, Yongjun, Liang, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894725/
https://www.ncbi.nlm.nih.gov/pubmed/29670349
http://dx.doi.org/10.2147/IJN.S151233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894725/
https://www.ncbi.nlm.nih.gov/pubmed/29670349
http://dx.doi.org/10.2147/IJN.S151233

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