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Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner

BACKGROUND: One of the most common side effects of paclitaxel was dosage-dependently painful neuropathy. Various reports indicated that spinal neuroinflammation was involved in paclitaxel-induced neuropathic pain. This study investigated the effect of icariin on paclitaxel-induced neuroinflammation...

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Detalles Bibliográficos
Autores principales: Gui, Yulong, Zhang, Jie, Chen, Liang, Duan, Shunyuan, Tang, Jing, Xu, Wei, Li, Aiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894904/
https://www.ncbi.nlm.nih.gov/pubmed/29623757
http://dx.doi.org/10.1177/1744806918768970