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Aerobic exercise training differentially affects ACE C- and N-domain activities in humans: Interactions with ACE I/D polymorphism and association with vascular reactivity

INTRODUCTION: Previous studies have linked angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) polymorphism (II, ID and DD) to physical performance. Moreover, ACE has two catalytic domains: NH2 (N) and COOH (C) with distinct functions, and their activity has been found to be modulated by...

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Detalles Bibliográficos
Autores principales: Alves, Cléber Rene, Fernandes, Tiago, Lemos, José Ribeiro, Magalhães, Flávio de Castro, Trombetta, Ivani Credidio, Alves, Guilherme Barreto, da Mota, Glória de Fátima Alves, Dias, Rodrigo Gonçalves, Pereira, Alexandre Costa, Krieger, José Eduardo, Negrão, Carlos Eduardo, Oliveira, Edilamar Menezes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894927/
https://www.ncbi.nlm.nih.gov/pubmed/29629833
http://dx.doi.org/10.1177/1470320318761725