Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice

Crohn's disease (CD) represents a chronic inflammatory disorder of the intestinal tract. Several susceptibility genes have been linked to CD, though their precise role in the pathogenesis of this disorder remains unclear. Immunity-related GTPase M (IRGM) is an established risk allele in CD. We...

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Detalles Bibliográficos
Autores principales: Rogala, Allison R., Schoenborn, Alexi A., Fee, Brian E., Cantillana, Viviana A., Joyce, Maria J., Gharaibeh, Raad Z., Roy, Sayanty, Fodor, Anthony A., Sartor, R. Balfour, Taylor, Gregory A., Gulati, Ajay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894938/
https://www.ncbi.nlm.nih.gov/pubmed/29361512
http://dx.doi.org/10.1242/dmm.031070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894938/
https://www.ncbi.nlm.nih.gov/pubmed/29361512
http://dx.doi.org/10.1242/dmm.031070

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