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Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease

The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell polarity, with distinct apical and basolateral plasma membrane domains, is pivotal for both barrier formation and for the uptake and vectorial transport of nutrients. The establishment of cell polarity requi...

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Detalles Bibliográficos
Autores principales: Schneeberger, Kerstin, Roth, Sabrina, Nieuwenhuis, Edward E. S., Middendorp, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894939/
https://www.ncbi.nlm.nih.gov/pubmed/29590640
http://dx.doi.org/10.1242/dmm.031088