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Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease
The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell polarity, with distinct apical and basolateral plasma membrane domains, is pivotal for both barrier formation and for the uptake and vectorial transport of nutrients. The establishment of cell polarity requi...
Autores principales: | Schneeberger, Kerstin, Roth, Sabrina, Nieuwenhuis, Edward E. S., Middendorp, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894939/ https://www.ncbi.nlm.nih.gov/pubmed/29590640 http://dx.doi.org/10.1242/dmm.031088 |
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