Cargando…
Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis
RNA splicing factors are essential for the viability of all eukaryotic cells; however, in metazoans some cell types are exquisitely sensitive to disruption of splicing factors. Neuronal cells represent one such cell type, and defects in RNA splicing factors can lead to neurodegenerative diseases. Th...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894942/ https://www.ncbi.nlm.nih.gov/pubmed/29419415 http://dx.doi.org/10.1242/dmm.031583 |