Motor neuron degeneration correlates with respiratory dysfunction in SCA1

Spinocerebellar ataxia type 1 (SCA1) is characterized by adult-onset cerebellar degeneration with attendant loss of motor coordination. Bulbar function is eventually impaired and patients typically die from an inability to clear the airway. We investigated whether motor neuron degeneration is at the...

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Detalles Bibliográficos
Autores principales: Orengo, James P., van der Heijden, Meike E., Hao, Shuang, Tang, Jianrong, Orr, Harry T., Zoghbi, Huda Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894948/
https://www.ncbi.nlm.nih.gov/pubmed/29419414
http://dx.doi.org/10.1242/dmm.032623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894948/
https://www.ncbi.nlm.nih.gov/pubmed/29419414
http://dx.doi.org/10.1242/dmm.032623

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