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Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model

Mutations in the GJB2 gene [which encodes connexin 26 (Cx26)] are the most common causes of hereditary hearing loss in humans, and previous studies showed postnatal development arrest of the organ of Corti in different Cx26-null mouse models. To explore the pathological changes and the mechanism beh...

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Detalles Bibliográficos
Autores principales: Chen, Sen, Xie, Le, Xu, Kai, Cao, Hai-Yan, Wu, Xia, Xu, Xiao-Xiang, Sun, Yu, Kong, Wei-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5894950/
https://www.ncbi.nlm.nih.gov/pubmed/29361521
http://dx.doi.org/10.1242/dmm.033019