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Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

Ehrlichia chaffeensis, the causative agent of human monocytotropic ehrlichiosis, secretes several effector proteins that bind host DNA to modulate host gene expression. The tandem repeat protein 120 (TRP120), one of the largest effector proteins, has four nearly identical tandem repeat (TR) regions...

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Detalles Bibliográficos
Autores principales: Klema, Valerie J., Sepuru, Krishna Mohan, Füllbrunn, Nadia, Farris, Tierra R., Dunphy, Paige S., McBride, Jere W., Rajarathnam, Krishna, Choi, Kyung H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895000/
https://www.ncbi.nlm.nih.gov/pubmed/29641592
http://dx.doi.org/10.1371/journal.pone.0194891