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Fasudil improves endothelial dysfunction in rats exposed to chronic intermittent hypoxia through RhoA/ROCK/NFATc3 pathway

Endothelial dysfunction is one of the main pathological changes in Obstructive sleep apnoea (OSA). The Rho kinase (ROCK) pathway is associated with endothelial dysfunction. However, the interaction between ROCK and nuclear factor of activated T cells isoform c3 (NFATc3) in the development of this pa...

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Detalles Bibliográficos
Autores principales: Li, Jie-Ru, Zhao, Ya-Shuo, Chang, Yue, Yang, Sheng-Chang, Guo, Ya-Jing, Ji, En-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895022/
https://www.ncbi.nlm.nih.gov/pubmed/29641598
http://dx.doi.org/10.1371/journal.pone.0195604