Effects of genetic variants in the TSPO gene on protein structure and stability

The 18 kDa translocator protein (TSPO) is an evolutionary conserved cholesterol binding protein localized in the outer mitochondrial membrane. Expression of TSPO is upregulated in activated microglia in various neuroinflammatory, neurodegenerative, and neoplastic disorders. Therefore, TSPO radioliga...

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Detalles Bibliográficos
Autores principales: Milenkovic, Vladimir M., Bader, Stefanie, Sudria-Lopez, Daniel, Siebert, Ramona, Brandl, Caroline, Nothdurfter, Caroline, Weber, Bernhard H. F., Rupprecht, Rainer, Wetzel, Christian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895031/
https://www.ncbi.nlm.nih.gov/pubmed/29641545
http://dx.doi.org/10.1371/journal.pone.0195627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895031/
https://www.ncbi.nlm.nih.gov/pubmed/29641545
http://dx.doi.org/10.1371/journal.pone.0195627

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