DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice

Studies disrupting the chemokine pathway CX3CL1 (fractalkine)/ CX3CR1 have shown decreased atherosclerosis in animal models but the techniques used to interrupt the pathway have not been easily translatable into human trials. DNA vaccination potentially overcomes the translational difficulties. We e...

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Detalles Bibliográficos
Autores principales: Zhou, Jimmy Jianheng, Wang, Yuan Min, Lee, Vincent W. S., Zhang, Geoff Yu, Medbury, Heather, Williams, Helen, Wang, Ya, Tan, Thian Kui, Harris, David C. H., Alexander, Stephen I., Durkan, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895033/
https://www.ncbi.nlm.nih.gov/pubmed/29641559
http://dx.doi.org/10.1371/journal.pone.0195657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895033/
https://www.ncbi.nlm.nih.gov/pubmed/29641559
http://dx.doi.org/10.1371/journal.pone.0195657

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